mek1 2 inhibitor Search Results


90
Merck & Co mek1/2 inhibitor
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Axon Medchem LLC mek1 inhibitor pd184352
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Atriva Therapeutics GmbH mek1/2 inhibitor zapnometinib
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Kashiyama Industries selective mek1/2 inhibitor pimasertib
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MedKoo Inc mek1/2 inhibitor ro-5126766 (ro-512)
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Bayer AG mek1/2 inhibitor bay-869766 (refametinib)
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Tajima Shoji Co Ltd mek1/2-erk1/2
Mek1/2 Erk1/2, supplied by Tajima Shoji Co Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Bioconnect Systems Inc mek1&2 inhibitor pd0325901
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AbMole Bioscience small molecule kinases inhibitors pd-325901 (mek1/2)
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Wolters Kluwer Health noncompetitive atp inhibitor of mek1/2
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Merck & Co mek1/2 inhibitor pd98059
Inhibition of DC-SIGN expression by specific inhibitors of signaling pathways. DC-SIGN expression was detected on THP-1 cells differentiated by PMA, PMA plus IL-4, or PMA plus IL-4 treated with specific inhibitors (Helenalin, AG490, SB202190, and <t>PD98059).</t> (a), The relative levels of DC-SIGN mRNA detected by real-time PCR. The levels of DC-SIGN mRNA in PMA plus IL-4 treated THP-1 cells were valued as 100%, and used as a reference. *means P < 0.05; **means P < 0.01. (b), DC-SIGN expression on surface of THP-1 cells detected by flow cytometry. The percentage of positive cells (top number) and mean fluorescence intensity (number below) are shown.
Mek1/2 Inhibitor Pd98059, supplied by Merck & Co, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Federation of European Neuroscience Societies mek1/mek2 inhibitor selumetinib
Inhibition of DC-SIGN expression by specific inhibitors of signaling pathways. DC-SIGN expression was detected on THP-1 cells differentiated by PMA, PMA plus IL-4, or PMA plus IL-4 treated with specific inhibitors (Helenalin, AG490, SB202190, and <t>PD98059).</t> (a), The relative levels of DC-SIGN mRNA detected by real-time PCR. The levels of DC-SIGN mRNA in PMA plus IL-4 treated THP-1 cells were valued as 100%, and used as a reference. *means P < 0.05; **means P < 0.01. (b), DC-SIGN expression on surface of THP-1 cells detected by flow cytometry. The percentage of positive cells (top number) and mean fluorescence intensity (number below) are shown.
Mek1/Mek2 Inhibitor Selumetinib, supplied by Federation of European Neuroscience Societies, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Inhibition of DC-SIGN expression by specific inhibitors of signaling pathways. DC-SIGN expression was detected on THP-1 cells differentiated by PMA, PMA plus IL-4, or PMA plus IL-4 treated with specific inhibitors (Helenalin, AG490, SB202190, and PD98059). (a), The relative levels of DC-SIGN mRNA detected by real-time PCR. The levels of DC-SIGN mRNA in PMA plus IL-4 treated THP-1 cells were valued as 100%, and used as a reference. *means P < 0.05; **means P < 0.01. (b), DC-SIGN expression on surface of THP-1 cells detected by flow cytometry. The percentage of positive cells (top number) and mean fluorescence intensity (number below) are shown.

Journal: Journal of Biomedicine and Biotechnology

Article Title: Multiple Signaling Pathways Are Involved in the Interleukine-4 Regulated Expression of DC-SIGN in THP-1 Cell Line

doi: 10.1155/2012/357060

Figure Lengend Snippet: Inhibition of DC-SIGN expression by specific inhibitors of signaling pathways. DC-SIGN expression was detected on THP-1 cells differentiated by PMA, PMA plus IL-4, or PMA plus IL-4 treated with specific inhibitors (Helenalin, AG490, SB202190, and PD98059). (a), The relative levels of DC-SIGN mRNA detected by real-time PCR. The levels of DC-SIGN mRNA in PMA plus IL-4 treated THP-1 cells were valued as 100%, and used as a reference. *means P < 0.05; **means P < 0.01. (b), DC-SIGN expression on surface of THP-1 cells detected by flow cytometry. The percentage of positive cells (top number) and mean fluorescence intensity (number below) are shown.

Article Snippet: The NF- κ B inhibitor Helenalin, JAK2/3 inhibitor AG490, p38MAPK inhibitor SB202190, and the MEK1/2 inhibitor PD98059 were purchased from Merck (Gibbstown, USA) and used at 1 μ M (Hellenalin), 300 μ g/mL (AG490), 5 μ M (SB202190), and 50 μ M (PD98059).

Techniques: Inhibition, Expressing, Real-time Polymerase Chain Reaction, Flow Cytometry, Fluorescence